Members’ Publications

Members’ Publications

Major disparities in patient-reported adherence compared to objective assessment of adherence using mass spectrometry: A prospective study in a tertiary-referral hypertension clinic.
Curneen JMG, Rabbitt L, Browne D, O'Donoghue DF, Alansari Y, Harhen B, Ní Ghríofa A, Ferguson J, McEvoy JW, Lappin D, Finn DP, O'Shea PM, Dennedy MC
Br J Clin Pharmacol. 2023 Jul;89(7):1948-1955. doi: 10.1111/bcp.15292. Epub 2022 Mar 25.PMID: 35199372
The ability of pGCD59 to predict adverse pregnancy outcomes: a prospective study of non-diabetic pregnant women in Ireland.
Bogdanet D, Castillo MT, Doheny H, Dervan L, Luque-Fernandez MA, Halperin JA, O'Shea PM, Dunne FP
Acta Diabetol. 2023 Feb;60(2):211-223. doi: 10.1007/s00592-022-01983-z. Epub 2022 Oct 29.PMID: 36309618
The Role of Early Pregnancy Maternal pGCD59 Levels in Predicting Neonatal Hypoglycemia-Subanalysis of the DALI Study
Bogdanet D, Luque-Fernandez MA, Toth-Castillo M, Desoye G, O'Shea PM, Dunne FP, Halperin JA
J Clin Endocrinol Metab. 2022 Nov 23;107(11):e4311-e4319. doi: 10.1210/clinem/dgac498.PMID: 36054347
Maintaining glucose integrity ex-vivo: Impact of preanalytical specimen handling.
Islam MN, Lyons C, Griffin TP, Hamon S, Dunne FP, O'Shea PM
Ann Clin Biochem. 2023 Sep 7:45632231199374. doi: 10.1177/00045632231199374. Online ahead of print.PMID: 37626439
The Utility of plasma glycated CD59 in predicting postpartum glucose intolerance :a prospective study of women diagnosed with GDM during a period of universal GDM screening
Delia Bogdanet, Michelle Toth Castillo, Helen Doherty, Louise Dervan, Miguel Angel Luque-Fernandez, Jose Halperin, Paula M O'Shea, Fidelma P Dunne.
Diabetic Medicine. 2023;00:e15121.
Instructions on appropriate fasting prior to phlebotomy; effects on patient awareness, preparation, and biochemical parameters
Nélia S V Andrade, Sinead N Curtin, Ashiq Masih, Brid Fitzgibbon, Katie Herbert, Mary Gowen, Margaret Lehane, Seán J Costelloe
Diagnosis. 2023 Feb 10. doi: 10.1515/dx-2022-0131
The Causal Role of Vitamin D Deficiency in Worse Covid-19 Outcomes-Implications-for-Policy-and-Practice-Development
D.M. McCartney, P.M. O’Shea, M. Healy, J.B. Walsh, T.P. Griffin, C. Walsh, D.G. Byrne, R.A. Kenny, J.L. Faul
Vitamin D: determinants of status, indications for testing and knowledge in a convenience sample of Irish adults
Scully, H., Laird, E., Healy, M., Crowley, V., Walsh, J., & McCarroll, K.
British Journal of Nutrition, 1-11. doi:10.1017/S0007114523000168
Vitamin D intake and status in Ireland: a narrative review
Vitamin D intake and status in Ireland: A narrative review
Proceedings of the Nutrition Society, 1-15. doi:10.1017/S0029665123002185
Sublethal Hyperthermia Transiently Disrupts Cortisol Steroidogenesis in Adrenocortical Cells
Mullen N, Donlon PT, Sebek J, Duffy K, Cappiello G, Feely S, Warde KM, Harhen B, Finn DP, O'Shea PM, Prakash P, O'Halloran M, Dennedy MC
Endocrinology. 2023 Mar 13;164(5):bqad046. doi: 10.1210/endocr/bqad046. PMID: 36932649; PMCID: PMC10083206.
Medium Chain Acyl-CoA Dehydrogenase Deficiency: 3 years of Newborn Screening
Howard C, Gorman I, Crushell E, Knerr I, Hughes J, Boruah R, O'Grady L, Elsammak MY, Brady JJ, Monavari AA.
Ir Med J. 2023 Mar 23;116(3):743. PMID: 37010499
European Federation of Clinical Chemistry; Laboratory Medicine (EFLM) Working Group Preanalytical Phase (WG-PRE). Recommendation for the design of stability studies on clinical specimens.
Gomez-Rioja R, Von Meyer A, Cornes M, Costelloe S, Vermeersch P, Simundic AM, Nybo M, Baird GS, Kristensen GBB, Cadamuro J;
Clin Chem Lab Med. 2023 Apr 6. doi: 10.1515/cclm-2023-0221. Epub ahead of print. PMID: 37021544.
Calculated Globulin as a potential screening tool for paraproteinemia to aid in the early diagnosis of Multiple Myeloma
Aisling O’Brien, Alison Bransfield, Fiona O’Halloran, Vitaliy Mykytiv
Challenging gestational trophoblastic disease cases and mimics: An exemplar for the management of rare tumours
M. Hamid, C.M. Joyce, H.K. Carroll, C. Kenneally, S. Mulcahy, Mary-Kate O’Neill, J. Coulter, S. O’Reilly
Advances in the diagnosis and early management of gestational trophoblastic disease
Caroline M Joyce, Brendan Fitzgerald, Tommie V McCarthy, John Coulter, Keelin O'Donoghue
BMJ Medicine 2022;1:e000321. doi: 10.1136/bmjmed-2022-000321
Non-esterified fatty acids (NEFA): sample stability and effect of haemolysis and icterus.
Amy Gillick, Jennifer J Brady.
Clin Chem Lab Med. 2022 Dec 2. doi: 10.1515/cclm-2022-0891. PMID: 36453801 DOI: 10.1515/cclm- 2022-0891C
Reference intervals for clinical biochemistry and haematology tests during normal pregnancy.
Wendy Groenendijk, Delia Bogdanet, Louise Dervan, Oisin Finn, Md Nahidul Islam, Helen Doheny, Tomás P Griffin, Liam Blake, Mark Lyons, Mary Kilcooley, Janusz Krawczyk, Ruth Gilmore, Damian G Griffin, Geraldine Gaffney, Fidelma P Dunne, Paula M O'Shea.
Ann Clin Biochem. 2022 Nov;59(6):433-446. doi: 10.1177/00045632221128686.
Low socioeconomic status predicts vitamin D status in a cross-section of Irish children.
Scully H, Laird E, Healy M, Crowley V, Walsh JB, McCarroll K.
J Nutr Sci. 2022 Jul 25;11:e61. doi: 10.1017/jns.2022.57.
Cross-reactivity in assays for prolactin and optimum screening policy for macroprolactinaemia.
Smith TP, Kelly S, Fahie-Wilson MN.
Clin Chem Lab Med. 2022 Jun 17;60(9):1365-1372. doi: 10.1515/cclm-2022-0459.
Interference by macroprolactin in assays for prolactin: will the In Vitro Diagnostics Regulation lead to a solution at last?
Fahie-Wilson MN, Cobbaert CM, Horvath AR, Smith TP.
Clin Chem Lab Med. 2022 Jun 15;60(9):1350-1355. doi: 10.1515/cclm-2022-0460.
Remote capillary blood collection for HbA1c measurement during the COVID-19 pandemic: A laboratory and patient perspective.
Groenendijk WN, Griffin TP, Islam MN, Blake L, Wall D, Bell M, O'Shea PM.
Diabet Med. 2022 Aug;39(8):e14897. doi:10.1111/dme.14897.
The utility of first trimester plasma glycated CD59(pGCD59) in predicting gestational diabetes mellitus: A prospective study of non-diabetic pregnant women in Ireland.
Bogdanet D, Toth Castillo M, Doheny H, Dervan L, Angel Luque-Fernandez M, Halperin J, O'Shea PM, Dunne FP.
Diabetes Res Clin Pract. 2022 Jul 28;190:110023. doi: 10.1016/j.diabres.2022.110023.
Changes in the Leptin to Adiponectin Ratio Are Proportional to Weight Loss After Meal Replacement in Adults With Severe Obesity.
Rafey MF, Abdalgwad R, O'Shea PM, Foy S, Claffey B, Davenport C, O'Keeffe DT, Finucane FM.
Front Nutr. 2022 May 18;9:845574. doi: 10.3389/fnut.2022.845574.
Biochemical testing for inborn errors of metabolism: experience from a large tertiary neonatal centre.
Dunne E, O'Reilly D, Murphy CA, Howard C, Kelleher G, Suttie T, Boyle MA, Brady JJ, Knerr I, Khuffash AE.
Eur J Pediatr. 2022 Aug 10. doi: 10.1007/s00431-022-04588-4.
COVID-19 pandemic and vitamin D: rising trends in status and in daily amounts of vitamin D provided by supplements.
McKenna MJ, Lyons OC, Flynn MA, Crowley RK, Twomey PJ, Kilbane MT.
BMJ Open. 2022 Aug 4;12(8):e059477. doi: 10.1136/bmjopen-2021-059477.
Total plasma homocysteine measurement: Evaluation of the Abbott immunoassay, comparison with the JEOL ion exchange chromatography and investigation of its clinical utility.
Suen KFK, Lee GR, Finnegan M, Halton K, Borovickova I, Trench C, Fitzgibbon MC.
Pract Lab Med. 2022 Jul 14;32:e00295. doi: 10.1016/j.plabm.2022.e00295.
European Federation of Clinical Chemistry, Laboratory Medicine EFLM Working Group Accreditation, ISO/CEN standards WG-A/ISO. An approach for determining allowable between reagent lot variation.
van Schrojenstein Lantman M, Çubukçu HC, Boursier G, Panteghini M, Bernabeu-Andreu FA, Milinkovic N, Mesko Brguljan P, Linko S, Brugnoni D, O'Kelly R, Kroupis C, Lohmander M, Šprongl L, Vanstapel F, Thelen M;
Clin Chem Lab Med. 2022 Feb 16;60(5):681-688. doi: 10.1515/cclm2022-0083.
The Contribution of Oral and Inhaled Glucocorticoids to Adrenal Insufficiency in Asthma.
Brennan V, Martin-Grace J, Greene G, Heverin K, Mulvey C, McCartan T, Lombard L, Walsh J, Hale EM, Srinivasan S, O'Reilly MW, Thompson CJ, Costello RW, Sherlock M.J.
Allergy Clin Immunol Pract. 2022 Jun 10:S2213-2198(22)00580-3. doi: 10.1016/j.jaip.2022.05.031.
Adrenal insufficiency is common amongst kidney transplant recipients receiving maintenance prednisolone and can be predicted using morning cortisol.
Tomkins M, Martin-Grace J, Kennedy C, McEnroe O, Heverin K, Srinivasan S, Little D, Conlon P, De Freitas D, Denton M, Magee C, O'Seaghdha C, O'Reilly MW, Thompson CJ, Sherlock M.
Nephrol Dial Transplant. 2022 May 13:gfac044. doi: 10.1093/ndt/gfac044.
Quality of patient-reported outcome reporting in trials of diabetes in pregnancy: a systematic review.
Newman C, Kgosidialwa O, Dervan L, Bogdanet D, Egan AM, Biesty L, Devane D, O'Shea PM, Dunne FP.
Diabetes Res Clin Pract. 2022 Apr 25:109879. doi: 10.1016/j.diabres.2022.109879.
Understanding a Low Vitamin D State in the Context of COVID-19.
Walsh JB, McCartney DM, Laird É, McCarroll K, Byrne DG, Healy M, O'Shea PM, Kenny RA, Faul JL.
Pharmacol. 2022 Mar 4;13:835480. doi: 10.3389/fphar.2022.835480. eCollection 2022.
Major disparities in patient-reported adherence compared to objective assessment of adherence using mass spectrometry: A prospective study in a tertiary-referral hypertension clinic.
Curneen JMG, Rabbitt L, Browne D, O'Donoghue DF, Alansari Y, Harhen B, Ní Ghríofa A, Ferguson J, McEvoy JW, Lappin D, Finn DP, O'Shea PM, Dennedy MC.
Br J Clin Pharmacol. 2022 Feb 23. doi: 10.1111/ bcp.15292.
No effect of maternal calcium intake and bone resorption during pregnancy on offspring bone mineral density at age 5 years.
Curtin L, Conway MC, Kilbane MT, McKenna MJ, McAuliffe FM.
Osteoporos Int. 2022 May;33(5):1165-1170. doi: 10.1007/s00198-021-06250-5.
Experience of women on the Irish National Gestational Trophoblastic Disease Registry.
Joyce CM, Coulter J, Kenneally C, McCarthy TV, O'Donoghue K.
Eur J Obstet Gynecol Reprod Biol. 2022 Mar 28; 272:206-212. doi: 10.1016/j.ejogrb.2022.03.039.
Higher inflammation is associated with cardiometabolic phenotype and biochemical health in women with obesity.
Killeen SL, Byrne DF, Geraghty AA, Kilbane MT, Twomey PJ, McKenna MJ, Yelverton CA, Saldova R, Van Sinderen D, Cotter PD, Murphy EF, McAuliffe FM.
Ann Nutr Metab. 2022 Mar 18. doi: 10.1159/000522564.
Assessment of serum total 25- hydroxyvitamin D assays for Vitamin D External Quality Assessment Scheme (DEQAS) materials distributed at ambient and frozen conditions.
Sempos CT, Williams EL, Carter GD, Jones J, Camara JE, Burdette CQ, Hahm G, Nalin F, Duewer DL, Kuszak AJ, Merkel J, Hoofnagle AN, Lukas P, Cavalier É, DurazoArvizu RA, Crump PM, Popp C, Beckert C, Schultess J, Van Slooten G, Tourneur C, Pease C, Kaul R, Villarreal A, Ivison F, Fischer R, van den Ouweland JMW, Ho CS, Law EWK, Simard JN, Gonthier R, Holmquist B, Batista MC, Meadows S, Cox L, Jansen E, Khan DA, Robyak K, Creer MH, Kilbane M, Twomey PJ, Freeman J, Parker N, Yuan J, Fitzgerald R, Mushtaq S, Clarke MW, Breen N, Simpson C, Wise SA.
Anal Bioanal Chem. 2022 Jan;414(2):1015-1028. doi: 10.1007/s00216-021-03742-5.
Interlaboratory comparison of 25- hydroxyvitamin D assays: Vitamin D Standardization Program (VDSP) Intercomparison Study 2 - Part 2 ligand binding assays - impact of 25-hydroxyvitamin D2 and 24R,25- dihydroxyvitamin D3 on assay performance.
10.1007/s00216-021-03742-5. Wise SA, Camara JE, Burdette CQ, Hahm G, Nalin F, Kuszak AJ, Merkel J, Durazo-Arvizu RA, Williams EL, Popp C, Beckert C, Schultess J, Van Slooten G, Tourneur C, Pease C, Kaul R, Villarreal A, Batista MC, Pham H, Bennett A, Jansen E, Khan DA, Kilbane M, Twomey PJ, Freeman J, Parker N, Mushtaq S, Simpson C, Lukas P, Cavalier É, Sempos CT.
Anal Bioanal Chem. 2022 Jan;414(1):351-366. doi: 10.1007/ s00216-021-03577-0.
A cross-section observational study on the seroprevalence of antibodies to COVID-19 in patients receiving opiate agonist treatment.
Fenton F, Stokes S, Eagleton M.
Ir J Med Sci. 2022; 191(3): 1053–1058. doi: 10.1007/s11845-021-02660-w.
IGF-2 mediated hypoglycemia and the paradox of an apparently benign lesion: a case report & review of the literature
Mairead T Crowley, Eibhlin Lonergan, Peter O'Callaghan, Caroline M Joyce, M Morita, Niamh Conlon, Domhnall J O'Halloran
BMC Endocr Disord. 2022 Oct 27;22(1):262. doi: 10.1186/s12902-022-01175-4
Low socioeconomic status predicts vitamin D status in a cross-section of Irish children
Helena Scully, Eamon Laird, Martin Healy, Vivion Crowley, James Bernard Walsh, Kevin McCarroll
J Nutr Sci. 2022 Jul 25;11:e61. doi: 10.1017/jns.2022.57. eCollection 202
Comparison of ultrasound with biomarkers to identify large-for-gestational age in women screened for gestational diabetes mellitus
Eimer G O'Malley, Ciara M E Reynolds, Anne Killalea, Ruth O'Kelly, Sharon R Sheehan, Michael J Turner
J Matern Fetal Neonatal Med. 2022 Dec;35(25):6306-6311. doi: 10.1080/14767058.2021.1911993.
PRECISE Study Steering Group. SARS-CoV-2 Antibody Testing in Health Care Workers: A Comparison of the Clinical Performance of Three Commercially Available Antibody Assays.
Allen N, Brady M, Carrion Martin AI, Domegan L, Walsh C, Houlihan E, Kerr C, Doherty L, King J, Doheny M, Griffin D, Molloy M, Dunne J, Crowley V, Holmes P, Keogh E, Naughton S, Kelly M, O'Rourke F, Lynagh Y, Crowley B, de Gascun C, Holder P, Bergin C, Fleming C, Ni Riain U, Conlon N;
Microbiol Spectr. 2021 Oct 31;9(2):e0039121. doi: 10.1128/Spectrum.00391-21.
Reference values for C-reactive protein and procalcitonin at term pregnancy and in the early postnatal period.
Joyce CM, Deasy S, Abu H, Lim YY, O'Shea PM, O'Donoghue K.
Ann Clin Biochem. 2021 Sep;58(5):452-460. doi:10.1177/00045632211005807.
Management of transgender patients in Laboratory Information Management Systems -Moving on from binary and ternary logic.
Costelloe SJ, Hepburn S.
Ann Clin Biochem. 2021 Jul;58(4):264-266. doi:10.1177/0004563220984825.
Survey of patient perception of pre-analytical requirements for blood testing in the UK and RoI.
Hepburn S, Jankute M, Cornes MP, Rios NR, Stretton A, Costelloe SJ.
Ann Clin Biochem. 2021 Mar;58 (2):132-140. doi: 10.1177/0004563220982325.
A survey of practice in the management of haemolysis, icterus and lipaemia in blood specimens in the United Kingdom and Republic of Ireland.
Costelloe SJ, Rico Rios N, Goulding N, Mistry H, Stretton A, De la Salle B, Hepburn S, Thomas A, Atherton J, Cornes M.
Ann Clin Biochem. 2021 Dec 13:45632211059755. doi: 10.1177/00045632211059755.
How to meet ISO15189:2012 pre-analytical requirements in clinical laboratories? A consensus document by the EFLM WG-PRE.
Vermeersch P, Frans G, von Meyer A, Costelloe S, Lippi G, Simundic AM.
Clin Chem Lab Med. 2021 Jan 15;59(6):1047-1061. doi: 10.1515/cclm-2020-1859.
Therapeutic potential of long-acting opioids and opioid antagonists for SARS-CoV-2 infection.
Eagleton M, Stokes S, Fenton F, Keenan E.
Br J Anaesth. 2021 Dec;127(6):e212-e214. doi: 10.1016/ j.bja.2021.08.022.
Low vitamin B12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4 year longitudinal study.
Laird E, O'Halloran AM, Molloy AM, Healy M, Hernandez B, O'Connor D, Kenny RA, Briggs R.
Br J Nutr. 2021 Dec 13:1-22. doi: 10.1017/S0007114521004748.
Environmental causes of copper toxicity should not be forgotten in familial presentations.
Reeve JLV, Twomey PJ, Borovickova I.
J Clin Pathol. 2021 Nov;74(11):691. doi: 10.1136/jclinpath-2020-207362.
Sweat testing in the modern era: A national survey of sweat testing practice in the Republic of Ireland.
Maguire B, Blake O, Boran G, Borovickova I, Abdelfadil S, Murray C, Elnazir B, Linnane B.
2021 Oct 4:S1569- 1993(21)01417-X. doi: 10.1016/j.jcf.2021.09.012.
Observations from a teaching hospital in Ireland: changing from MDRD to CKD-EPI eGFR in routine practice.
Reeve JLV, Davis M, Twomey PJ.
J Clin Pathol. 2021 Sep;74(9):608-611. doi: 10.1136/ jclinpath-2020-206713.
Performance characteristics of five SARSCoV-2 serological assays: Clinical utility in health-care workers.
Heffernan E, Kennedy L, Hannan MM, Ramlaul N, Denieffe S, Courtney G, Watt A, Hurley J, Lynch M, Fitzgibbon M.
Ann Clin Biochem. 2021 Sep;58(5):496-504. doi: 10.1177/00045632211012728.
Bone resorption and dietary calcium in pregnancy-a window to future maternal bone health.
O'Brien EC, Geraghty AA, Kilbane MT, McKenna MJ, McAuliffe FM.
Osteoporos Int. 2021 Sep;32(9):1803-1814. doi: 10.1007/s00198-021-05891-w.
Vitamin D retesting by general practitioners: a factor and cost analysis.
Scully H, Laird E, Healy M, Crowley V, Walsh JB, McCarroll K.
Clin Chem Lab Med. 2021 Jul 19;59(11):1790-1799. doi: 10.1515/ cclm-2021-0607.
A Comparison of the Performance of SARS-CoV-2 Antibody Assays in Healthcare Workers with COVID-19.
Kerr C, Dunne J, Hughes G, Cox F, Healy M, Holmes P, O'Rourke F, O'Brien C, Coyne D, Crowley V, Crowley B, Conlon N, Bergin C.
Ir Med J. 2021 Aug 19;114(7):414.
Discordant Thyroid Function Tests at First Presentation of Panhypopituitarism-A & "Reversible Cause" of Cognitive Decline?
McDonnell T, Farrell A, O'Shea PM, Mulkerrin EC.
J Appl Lab Med. 2021 Jul 7;6(4):1045-1050. doi: 10.1093/jalm/jfaa146.
On the association between circulating biomarkers and atherosclerotic calcification in a cohort of arterial disease participants
Cahalane RM, Barrett HE, Ross AM, Mulvihill JJE, Purtill H, Selvarajah L, O'Brien J, Kavanagh EG, Moloneye MA, Egan SM, Leahy FC, Griffin TP, Islam MN, O'Shea PM, Walsh MT, O'Connor EM.
Nutr Metab Cardiovasc Dis. 2021 May 6;31(5):1533-1541. doi: 10.1016/j.numecd.2021.02.005.
The presentation of congenital adrenal hyperplasia in an unscreened population.
Conlon TA, Hawkes CP, Brady JJ, Murphy NP.
J Pediatr Endocrinol Metab. 2021 Jun 25;34(9):1123-1129. doi: 10.1515/jpem-2021-0123.
Lipid reference values in an Irish population.
Hughes D, Crowley J, O'Shea P, McEvoy JW, Griffin DG.
Ir J Med Sci. 2021 Feb;190(1):117-127. doi: 10.1007/s11845-020-02309-0.
A proposed Common Training Framework for Specialists in Laboratory Medicine under EU Directive 2013/55/EC (The Recognition of Professional Qualifications).
Wieringa G, Queraltó J, Homšak E, Jassam N, Cavalier E, Svinarov D, Krleža JL, Christou S, Pikner R, Larsen TR, Tomberg K, Linko-Parvinen A, Sapin V, Baum H, Kroupis C, Bagoly Z, Costelloe S, Sciacovelli L, Stasulans J, Vitkus D, Meunier D, Solnica B, Reguengo H, Mambet C, Kovac G, Krhin B, Ohlson M, Buhagiar G, Simundic AM.
Clin Chem Lab Med. 2020 Nov 30;59(3):505-512. doi: 10.1515/cclm-2020 -1504.
COVID-19 in adults: test menu for hospital blood science laboratories.
Paula M O'Shea, Graham Robert Lee, Tomás P Griffin, Vincent Tormey, Amjad Hayat, Seán J Costelloe, Damian Gerard Griffin, Saradha Srinivasan, Maurice O'Kane, Conor M Burke, John Faul, Christopher J Thompson, Gerard Curley, William P Tormey.
Ir J Med Sci. 2020 Nov;189(4):1147-1152. doi: 10.1007/s11845-020-02252-0.

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